[Download] "Eps[R] 7630-Solution--an Effective Therapeutic Option in Acute and Exacerbating Bronchitis (Pelargonium Sidoides) (Clinical Report)" by Phytomedicine: International Journal of Phytotherapy & Phytopharmacology # Book PDF Kindle ePub Free

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Title: Eps[R] 7630-Solution--an Effective Therapeutic Option in Acute and Exacerbating Bronchitis (Pelargonium Sidoides) (Clinical Report)
Author : Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
Release Date : January 01, 2007
Genre: Life Sciences,Books,Science & Nature,
Pages : * pages
Size : 206 KB

Description

Abstract Acute bronchitis is one of the most common diagnoses in ambulatory care medicine. Although the benefit of antibiotics for acute bronchitis, which is mostly virally induced, is disputed, they are often prescribed. A therapeutic option for respiratory tract infections that do not fall within the strict indication range for antibiotic administration is the liquid herbal drug preparation from the roots of Pelargonium sidoides, EPs[R] 7630 (Umckaloabo[R]), which has been tested against placebo in double-blind clinical trials. EPs[R] 7630 has both antibacterial and immuno-modulating properties. The efficacy and tolerability of EPs[R] 7630 was investigated in a prospective, open, multicentric outcomes study with 205 patients suffering from acute bronchitis or acute exacerbation of chronic bronchitis. The main outcome measure was the change in the total score of five symptoms typical for bronchitis (cough, expectoration, wheezing/whistling on expiration, chest pain during coughing, and dyspnoea), which were each rated using a 5-point scale (from 0 = not present to 4 = extremely pronounced). Further symptoms (hoarseness, headache, aching limbs and fatigue) were assessed using a four-point scale (from 0 = not present to 3 = very pronounced). The total score of the typical bronchitis symptoms amounted to 6.1[+ or -]2.8 points on average at the start of treatment and decreased by 3.3[+ or -]3.8 points to 2.8[+ or -]2.6 points by the final examination on day 7. About 60.5% of the patients assessed their health condition at the end of the study as much improved or free from symptoms. The onset of action appeared after two days on average. Adverse events occurred in a total of 16 patients. There were no serious adverse events. Altogether, 78% of the patients were satisfied or very satisfied with the treatment.